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Introduction to Medicinal Chemistry

Explores the basic concepts of medicinal chemistry. An understanding of structure and stereochemistry and of chirality and drug design is developed. Drug activity is discussed in general terms of structure-activity relationships such as observed in the interaction of enzymes with substrates and inhibitors, and receptors with agonists and antagonists. Selective drugs and their mode of action include sulfa drugs, B-lactam antibiotics, agents to control Parkinson?s disease and anticancer drugs. PREREQ: CHMI 2427 and 2227. (lec 3) cr 3 Lecture (3.00).

School of Natural Sciences